Diffuse Alveolar Hemorrhage. A Rare Initial Manifestation of Juvenile Onset Systemic Lupus Erythematosus with Novel Therapeutic Options: Case Report and Review of Literature

INTRODUCTION: Juvenile onset systemic lupus erythematosus (JSLE) is a rare disease entity, characterized by a wide spectrum of organ involvement. Inclusive of these is a rare manifestation with high mortality known as diffuse alveolar hemorrhage (DAH). JSLE presenting with DAH presents a therapeutic challenge for both the rheumatologist and the intensivist, requiring careful attention to the underlying pathophysiology of widespread inflammation and …