HISTOPATHOLOGICAL EXAMINATION OF PLACENTA IN CASES OF REPRODUCTIVE FAILURE

The placenta signifies the "second" or "embryonic" period of pregnancy (after the implantation period) and describes the establishment of a fully functional placenta. The placenta is an apposition of fetal and parental tissue for the purposes of physiological exchange. The placenta is a unique organ with dual blood circulation, functioning throughout foetal development. Placental trophoblasts express and produce coagulation components, participating not only in haemostasis but also in placental vascular development and differentiation 1 . The earlier insight into this organ comes from drawing from illustrators such as Andreas Vesalius (1514-1564). The designation “placenta” was introduced by Gabriele de Falloppio (1523-1562). Others, however believe that this designation, placenta, stemmed from Realdus Columbus in 1559.