Lupus activity in a patient with end-stage renal disease: A case report

Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple organs, and renal involvement is found in 50% of patients and is variable according to racial and ethnic group. It is estimated that 10% of patients with lupus nephritis (NL) develop end-stage renal disease (ERT), and once progression occurs, 80% of patients are negative for activity markers. However, although it is rare, the reactivation of the disease can occur in advanced renal involvement, and it is important to diagnose it in a timely manner to define the cause and treat it, avoiding complications. The clinical case is presented of a 45-year-old patient, with ERT on peritoneal dialysis, who was in remission of the disease and subsequently developed lupus activity.