The Synthesis of 2,3-Ring-Fused Analogues of 7-Fluoro-1-methyl-3-(methylsulfinyl)-4(1H)-quinolinone

The lithium enolate of cyclic β-oxo sulfides has been shown to react with selected isatoic anhydrides to afford novel 9-oxothieno-, 10-oxothiopyrano- and 11-oxothiepino[3,2-b]quinolines. These cyclic sulfide compounds were then oxidized with 3-chloroperoxybenzoic acid to afford either the corresponding 1-oxides or 1,1-dioxides