Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity

Alireza Labani-Motlagh,Pernilla Israelsson,Ulrika Ottander,Eva Lundin,Ivan Nagaev,Olga Nagaeva,Eva Dehlin,Vladimir Baranov,Lucia Mincheva-Nilsson

Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity

2016

Alireza Labani-Motlagh
Pernilla Israelsson
Ulrika Ottander
Eva Lundin
Ivan Nagaev
Olga Nagaeva
Eva Dehlin
Vladimir Baranov
Lucia Mincheva-Nilsson

Cancers constitutively produce and secrete into the blood and other biofluids 30-150 nm-sized endosomal vehicles called exosomes. Cancer-derived exosomes exhibit powerful influence on a variety of ...

Keywords:

NK Cell Lectin-Like Receptor Subfamily K
Endosome
Cancer research
dNaM
Microvesicles
NKG2D
Cytotoxicity
Signal transduction
Cell biology
Biology
Receptor

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