Coronary Artery Bypass Surgery in Left Main Disease with Idiopathic Artery Pulmonary Hypertension . Role of PGE Therapy

Introduction Idiopathic pulmonary hypertension (PAH) is a rare disease of unknown etiology that leads to the development of severe precapillary pulmonary hypertension [ 1 - 3 ], characterized by impaired regulation of both pulmonary hemodynamics and vascular growth.’ The responsiveness to vasodilator therapy in patients with PAH varies considerably [ 4 , 5 ]. Coronary artery bypass grafting (CABG) with extracorporeal circulation has a deleterious effect on lung tissues.