Inhibition of Complementary Lysis by Rheumatoid Sera

IN suitable conditions, anti-γ-globulin inhibits lysis of sensitized red cells1. Rheumatoid factor is apparently an antibody against γ-globulin, and so it might be expected to do the same. This report describes the results of “inhibition of lysis” titrations on sera from normal subjects and patients with rheumatoid arthritis, and shows that the correlation with sensitized sheep cell agglutination tests and latex fixation tests is high.