Mild hypoglycaemic attacks induced by sulphonylureas related to CYP2C9, CYP2C19 and CYP2C8 polymorphisms in routine clinical setting

Osman Gökalp,Arzu Gunes,Hakan Çam,Erkan Cure,Osman Aydin,Mehmet Numan Tamer,Maria Gabriella Scordo,Marja-Liisa Dahl

Mild hypoglycaemic attacks induced by sulphonylureas related to CYP2C9, CYP2C19 and CYP2C8 polymorphisms in routine clinical setting

2011

Osman Gökalp
Arzu Gunes
Hakan Çam
Erkan Cure
Osman Aydin
Mehmet Numan Tamer
Maria Gabriella Scordo
Marja-Liisa Dahl

Aim To evaluate the impact of polymorphisms in the cytochrome P450 (CYP) 2C9, 2C19 and 2C8 genes on the risk of mild hypoglycaemic attacks in patients treated with sulphonylureas.

Keywords:

Anesthesia
CYP2C9
Diabetes mellitus
Gliclazide
Cytochrome P450
Glimepiride
Medicine
CYP2C8
Glipizide
Pharmacology
CYP2C19
in patient
Internal medicine

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