G2-Phase Arrest Through p21(WAF1 / Cip1) Induction and cdc2 Repression by Gnidimacrin in Human Hepatoma HLE Cells

Mitsuzi Yoshida,Yuki Matsui,Akira Iizuka,Yoshinori Ikarashi

G2-Phase Arrest Through p21(WAF1 / Cip1) Induction and cdc2 Repression by Gnidimacrin in Human Hepatoma HLE Cells

2009

Mitsuzi Yoshida
Yuki Matsui
Akira Iizuka
Yoshinori Ikarashi

Gnidimacrin (NSC252940) shows significant antiproliferating activity against human tumor cell lines. This compound binds to and directly activates protein kinase C

Keywords:

Psychological repression
Enzyme
Cancer research
Protein kinase C
Liver cancer
Tumor suppressor gene
CDKN1A Gene
Cyclin-dependent kinase 1
Biology
Cell culture

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