ACTN3 R577X Polymorphism Is Associated With the Incidence and Severity of Injuries in Professional Football Players

Objective:The ACTN3 R577X gene variant results in the absence of the α-actinin-3 protein in ∼18% of humans worldwide and has been associated with athletic performance and increased susceptibility to eccentric muscle damage. The aim of this study was to investigate the association between ACTN3 R577X