IL‐21 promotes myocardial ischaemia/reperfusion injury through the modulation of neutrophil infiltration

Kejing Wang,Shuang Wen,Jiao Jiao,Ting-Ting Tang,Xin Zhao,Min Zhang,Bing-Jie Lv,Yuzhi Lu,Xingdi Zhou,Jingyong Li,Shaofang Nie,Yuhua Liao,Qing Kenneth Wang,Xin Tu,Ziad Mallat,Ni Xia,Xiang Cheng

IL‐21 promotes myocardial ischaemia/reperfusion injury through the modulation of neutrophil infiltration

2018

Kejing Wang
Shuang Wen
Jiao Jiao
Ting-Ting Tang
Xin Zhao
Min Zhang
Bing-Jie Lv
Yuzhi Lu
Xingdi Zhou
Jingyong Li
Shaofang Nie
Yuhua Liao
Qing Kenneth Wang
Xin Tu
Ziad Mallat
Ni Xia
Xiang Cheng

Background and Purpose The immune system plays an important role in driving the acute inflammatory response following myocardial ischaemia/reperfusion injury (MIRI). IL‐21 is a pleiotropic cytokine with multiple immunomodulatory effects, but its role in MIRI is not known.

Keywords:

Endocrinology
Internal medicine
Pathology
Ischaemia-reperfusion injury
Chemistry
Infiltration (hydrology)
Reperfusion injury
Chemokine
p38 mitogen-activated protein kinases
CXCL1
CXCL2
Cytokine
Protein kinase B
Pharmacology
Cardiac function curve

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations