Population pharmacokinetics of darbepoetin alfa in peritoneal dialysis and non-dialysis patients with chronic kidney disease after single subcutaneous administration

Kazuki Kawakami,Hirotaka Takama,Daisuke Nakashima,Hideji Tanaka,Eiji Uchida,Tadao Akizawa

Population pharmacokinetics of darbepoetin alfa in peritoneal dialysis and non-dialysis patients with chronic kidney disease after single subcutaneous administration

2009

Kazuki Kawakami
Hirotaka Takama
Daisuke Nakashima
Hideji Tanaka
Eiji Uchida
Tadao Akizawa

Objective To characterize the pharmacokinetics of darbepoetin alfa and covariate relationships in chronic kidney disease (CKD) patients after a single subcutaneous administration.

Keywords:

Erythropoietin
Dialysis
Anesthesia
Urology
Diabetes mellitus
Darbepoetin alfa
Medicine
Population
Kidney disease
Peritoneal dialysis
Surgery
Pharmacokinetics
dialysis patients
population pharmacokinetics
NONMEM

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