Contraste entre dos esquemas de antibióticos en niños con choque séptico por «fiebre manchada de las Montañas Rocosas» (Contrasting two antibiotics schemes in children with septic shock spotted fever of the Rocky Mountains)

2014 
Palabras clave: Fiebre manchada de las Montanas Rocosas, Rickettsia rickettsii, shock septico, antibioticos, FMMR. SUMMARY Objective: To compare two treatment guidelines to differ in handling antibiotics in patients with septic shock Spotted Fever Rocky Mountain (RMSF). Material and methods: Design; cases and controls. We compare 2 samples at the convenience of the records of 40 patients in septic shock by RMSF treated based on a therapeutic guide that should fix septic shock considering the combination of ciprofloxacin - doxycycline, with a control group of 20 patients with RMSF treated using doxycycline plus ceftriaxone. Results: Correction of serum lactate was achieved in 85% in the study group compared to 10% in the control group, p = 0.04. Mean arterial pressure (MAP) in the study group at 90% compared to 20% in the control group p = 0.03. Mortality and correction of platelet count there was no significant difference p = 0.23 and 0.28 respectively in 48 hours. Conclusions: The management of septic shock by RMSF study group showed better stabilization within 48 hours.
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