SOLID PHASE SYNTHESIS OF 2-SUBSTITUTED BENZOFURANS VIA THE PALLADIUM-CATALYSED HETEROANNULATION OF ACETYLENES

Abstract The copper/palladium-promoted heteroannulation of terminal acetylenic compounds in the presence of resin bound ortho-hydroxy aryl iodides is described. The process produces 2-substituted benzofuran derivatives in good yield and high purity.