VLA-4 and CXCR4 overexpression in bone marrow of an aleukemic B-cell acute lymphoblastic leukemia presenting with osteolytic bone lesions

Acute B-lymphoblastic leukemia (B-ALL) is usually characterized by a hyperleukocytosis together with infiltration of the bone marrow (BM) and lymphoid organs. Occasionally, extralymphatic B-ALL man...