Differentiation of optical active form and racemic form of amphetamine-type stimulants by terahertz spectroscopy

Abuse of amphetamine-type stimulant (ATS) is increased in Japan. Most ATS has optical isomers and their stimulatory effects are different between optical active forms and racemic form. We applied terahertz spectroscopy to differentiate the optical active form and racemic form in solid phase. Most of spectra of two different forms showed different spectral pattern and terahertz spectroscopy can be useful for differentiation of optical isomers from racemic form.