Acyclovir composition freeze-dried tablet and preparation method thereof

2014 
The invention provides an acyclovir composition freeze-dried tablet and a preparation method thereof, and relates to the technical field of medicines and medicine production. The acyclovir composition freeze-dried tablet comprises acyclovir, starch and cane sugar, wherein the starch and the cane sugar are taken as auxiliary materials. Common corn starch is treated by a heating process, so that the bonding and disintegration functions of the starch in the tablet can be improved, and the formability of the tablet is improved. The acyclovir composition freeze-dried tablet only needs two auxiliary materials namely the starch and the cane sugar. The acyclovir composition freeze-dried tablet adopts the freeze-drying process that temperature is reduced and increased for two times respectively, and the process that temperature is reduced and increased for two times enables the formability of the tablet to be better and increases the dissolution rate of the tablet so as to improve the biological availability of the tablet; the tablet overcomes the defects of a common acyclovir tablet, the types and dosage of auxiliary materials in the acyclovir tablet are reduced, the dissolution rate of the tablet is high, the biological availability of the tablet is high, and the curative effect and the safety of clinical medication are ensured.
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