Incidence, Risk Factors, and Trends for Post-Heart Transplantation Diabetes Mellitus

ABSTRACT This retrospective study analyzed glycemic trends, incidence of post-transplant diabetes mellitus (PTDM) incidence and associated risk factors in a cohort of patients undergoing first-time heart transplantation (HT). Univariate analyses compared patients with and without pre-transplant diabetes mellitus (DM). Multivariate regression analyses were conducted to determine association between PTDM and different risk factors. Finally, trends in glucometrics and other outcomes are described across follow-up times points. There were 152 patients who underwent HT between 2010 and 2015, 109 of whom had no pre-transplant history of DM. PTDM incidence was 38% by the 1-year follow-up. Pre-transplant body mass index (OR 1.12, 95% CI 1.01 – 1.23, p=.03), insulin use during the final 24 hours of inpatient stay (OR 4.26, 95% CI 1.72-10.56, p