Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly

Razvan V. Chereji,Vasudha Bharatula,Nils Elfving,Jeanette Blomberg,Miriam Larsson,Alexandre V. Morozov,James R. Broach,Stefan Björklund

Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly

2017

Razvan V. Chereji
Vasudha Bharatula
Nils Elfving
Jeanette Blomberg
Miriam Larsson
Alexandre V. Morozov
James R. Broach
Stefan Björklund

Mediator is a multi-unit molecular complex that plays a key role in transferring signals from transcriptional regulators to RNA polymerase II in eukaryotes. We have combined biochemical purificatio ...

Keywords:

Immunoprecipitation
Chromatin remodeling
Actin
Molecular biology
Genetics
MED1
DNA
Gene
RNA polymerase II
Cell biology
Mediator
Biology
RNA
DNA-binding protein

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