Arginine or Guanidinoacetic Acid Can Serve as Precursors for Creatine Synthesis in Parenteral Nutrition, but Only with Excess Methionine to Facilitate Transmethylation

Scott D. Bray,Alaa Aljaroudi,O. Chandani Dinesh,Thillayampalam Kankayaliyan,Janet A. Brunton,Robert F. Bertolo

Arginine or Guanidinoacetic Acid Can Serve as Precursors for Creatine Synthesis in Parenteral Nutrition, but Only with Excess Methionine to Facilitate Transmethylation

2016

Scott D. Bray
Alaa Aljaroudi
O. Chandani Dinesh
Thillayampalam Kankayaliyan
Janet A. Brunton
Robert F. Bertolo

Creatine synthesis in neonates demands high amounts of its precursors, arginine and methionine. Parenteral nutrition (PN) is typically marginal in these amino acids and devoid in creatine. The pres...

Keywords:

Transmethylation
Endocrinology
Arginine
Diabetes mellitus
Creatine synthesis
Biochemistry
Methionine
Internal medicine
Biology
Parenteral nutrition
Creatine
Amino acid

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