Abstract 11545: Mechanism of Chronic Phosphodiesterase Type 5 Inhibition-Caused Regression of Heart Failure: Beneficial Effects of Left Ventricular and Myocyte Function, [Ca2+]i Regulation and Beta-Adrenergic Modulation

Tiankai Li,Qun Shao,Heng-Jie Cheng,Michael F. Callahan,Wei Min Li,Che-Ping Cheng

Abstract 11545: Mechanism of Chronic Phosphodiesterase Type 5 Inhibition-Caused Regression of Heart Failure: Beneficial Effects of Left Ventricular and Myocyte Function, [Ca2+]i Regulation and Beta-Adrenergic Modulation

2013

Tiankai Li
Qun Shao
Heng-Jie Cheng
Michael F. Callahan
Wei Min Li
Che-Ping Cheng

Background: Phosphodiesterase type 5 (PDE5) inhibition (I) has been shown to exert profound beneficial effects in heart failure (HF). However, the mechanisms are not completely understood. It remai...

Keywords:

Cardiology
Diabetes mellitus
cGMP-specific phosphodiesterase type 5
Myocyte
Heart failure
Internal medicine
Adrenergic receptor
Medicine
beneficial effects
Calcium
Ventricular remodeling
Endocrinology

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