Long-term clinical course and outcome of schizophrenia in rural Ethiopia : 10-year follow-up of a population-based cohort

2015 
article i nfo Background: Although the few available studies from LMICs report favorable outcome, the course of schizophre- nia is more complex than has been indicated so far. Methods: A sample of 361 people with a standardized clinical diagnosis of schizophrenia were recruited from a predominantly rural community in Ethiopia and followed up regularly for an average of 10 years. Psychiatrists used the Longitudinal Interval Follow-up Evaluation chart to carry out assessment of illness course. Duration of time in clinical remission was the primary outcome. Result: About 61.0% of the patients remained under active follow-up, while 18.1% (n = 65) were deceased. The mean percentageof follow-up time in complete remission was 28.4% (SD = 33.0). Female patients were sig- nificantly more likely to have episodic illness course with no inter-episode residual or negative symptoms (χ
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