Increased microRNA-221/222 and decreased estrogen receptor α in the cervical portion of the uterosacral ligaments from women with pelvic organ prolapse

Introduction and hypothesis The aim of this study was to compare the expression of microRNA (miR)-221, miR-222, and estrogen receptor α (ERα) in the uterosacral ligaments of women with and without pelvic organ prolapse (POP).