Real-Time EM-Tracking Based Treatment Platform for High Dose Rate Prostate Brachytherapy: End-to-End Validation and Clinical Workflows

F(r,q) exhibited dramatic reduction between the forward (0 ) and rearward (180 ) directions. This effect diminished from a factor of 270 at r50.1 cm, 23 at r51 cm, and 5.1 at r510 cm. The highest dose gradient occurred in contact with the device at 92 where dose changed by a factor of 3 within 1 due to Au foil shielding. CivaSheet commissioning within the VariSeed 9.0 TPS over 91 datapoints from 0.1#r#11cm and 0 #q#180 demonstrated reproducibility of input data within 2% except at the highest dose gradient where TPS linear interpolations resulted in a 3.1% difference compared to input data. Dose superposition of a single CivaDot replicated the dose distribution of a multi-source CivaSheet array with! 2% differences, except at locations where another CivaDot was present. In clinical practice, the device would not be perfectly planar and the accuracy provided by utilizing dose superposition through geometric repositioning of CivaDots supersedes TPS limitations of intersource radiation scatter and shielding effects.