Profile susceptibility to fluconazole and voriconazole antifungals by species of Candida albicans isolated from urine culture

Background The term candiduria can be defined as the observation of yeasts on direct examination of urine through the presence of pseudo-hyphae and fungal growth in urine culture [1]. The yeast Candiduria can be detected in the urine in patients who have bladder colonization and in patients who have urinary tract infection [2]. Currently, there are few options in the medicine antifungal market for the treatment of urinary tract infections. And the most used are amphotericin B, ketoconazole, fluconazole and voriconazole. Therefore, the determination of the profile of antifungal susceptibility among isolates of C. albicans urine in patients, it is so important as epidemiological marker that serves to guide therapeutic procedures [3]. Thus, many methods have been tested as alternative to the antifungal susceptibility, as the method of agar disk diffusion M44-A12. So, this study aimed to evaluate the antifungal susceptibility profile of Candida albicans isolated from the urine of patients admitted at the university hospital in Dourados MS.