A Belgian Randomized Trial in Hepatitis C Virus-Infected Patients with Persistently Normal Alanine Aminotransferase

Persistently normal alanine aminotransferase (PNALT) is present in 30 to 40% of chronic hepatitis patients and it is generally accepted that they have no liver damage. However, some studies suggest that there are some degrees of mild to moderate histological liver damage. We evaluated the fibrosis stage and the virological outcome in treated patients with PNALT.