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Tendon Healing with Growth Factors

2012 
The incidence of sport injuries has increased in recent years due to fitness training and growing participation in sport activities by the general public. The tendon rupture was regarded as an injury typical of high-performance athletes. As physical and recreational activities become more and more popular followed by an increased frequency of soft tissue injuries, health care costs are raising. Tendon lacerations, ruptures, or inflammation cause marked morbidity and has a major impact on work, recreational activities, and daily needs. Tendon ruptures and tears are slow healing injuries that are often treated surgically with unsatisfactory results for some patients. As biology of healing processes and the influence of growth factors are becoming more and more clear, one can consider introducing biological therapy into clinical use. For optimizing treatment more understanding is needed. Therefore tendon physiology, pathology, ruptures biology and functionality, normal healing process, as well as the role of polypeptide factors during healing need to be known.
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