The Relation Between Septic Shock and Glycemic Control In Critically Ill Patients In Benha University Hospitals

Hyperglycemia is common event in critical unit including patients with or without history of diabetes . in patients with septic shock , blood glucose level easily elevated by complex of pathophysiological mechanisms , we investigate the effect of normalization of blood glucose  in septic shock patients including the morbidity , the mortality, the length of icu stay and the time on mechanical ventilation We included 60 patients divided into two groups.Group1:consist of 30 patients was applied to intensive glycemic control. Group 2: consist of 30 patients was applied to conventional glycemic control. We found that strict normalization of blood glucose have favourable outcome than conventional control in morbidity but not mortality. 20 % in group 1 needed hemodialysis and 80 % of patients required hemodialysis in group 2  which is statistically highly significant.  Mortality rate  60% in group 1 and 80% in group 2 which is statistically insignificant. We found that intensive glycemic control have more favourable effects on patient morbidity but have no effect on mortality The misuse of antibiotic and the co-morbidities have direct negative effect in the response to medication and the progression of the disease Hypoglycemia is noticed more in intensive study.