Enhancement of CURB65 score with proadrenomedullin (CURB65-A) for outcome prediction in lower respiratory tract infections: Derivation of a clinical algorithm

Werner C. Albrich,Frank Dusemund,Kristina Rüegger,Mirjam Christ-Crain,Werner Zimmerli,Thomas Bregenzer,Sarosh Irani,Ulrich Buergi,Barbara Reutlinger,Beat Mueller,Philipp Schuetz

Enhancement of CURB65 score with proadrenomedullin (CURB65-A) for outcome prediction in lower respiratory tract infections: Derivation of a clinical algorithm

2011

Werner C. Albrich
Frank Dusemund
Kristina Rüegger
Mirjam Christ-Crain
Werner Zimmerli
Thomas Bregenzer
Sarosh Irani
Ulrich Buergi
Barbara Reutlinger
Beat Mueller
Philipp Schuetz

Proadrenomedullin (ProADM) confers additional prognostic information to established clinical risk scores in lower respiratory tract infections (LRTI). We aimed to derive a practical algorithm combining the CURB65 score with ProADM-levels in patients with community-acquired pneumonia (CAP) and non-CAP-LRTI.

Keywords:

Respiratory tract infections
Pathology
Intensive care medicine
Framingham Risk Score
Community-acquired pneumonia
Lower respiratory tract infection
Medicine
Pneumonia severity index
Algorithm
clinical algorithm
Medical microbiology
Derivation
Predictive value of tests
Cohort study

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