Different Transmissibility of 2 Isolates of Seoul Virus from the Same Wild Brown Rat (Rattus norvegicus)

Two Seoul virus strains were isolated from the same wild brown rat (Rattus norvegicus) by 2 different procedures. While one isolate (TR-352) by means of a cell culture system had no horizontal transmissibility in 3-week-old rats, another isolate (TR-352R) by means of inoculation to newborn rats had transmissibility in rats.