The development of a clinic for the management of depression and anxiety: the Depression and Anxiety Research and Treatment (DART) Clinical Program

2000 
In developed nations as reported in 1996, mental dis-orders contributed 17% of the total burden of disease, with affective dis-orders accounting for 7.7% and anxiety disorders 2.3% to this figure.The high level of psychiatric comorbidity in patients with mood andanxiety disorders has also been well documented.
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