Harmonin inhibits presynaptic Cav1.3 Ca2+ channels in mouse inner hair cells
2011
Harmonin was previously identified as a scaffolding protein that is important for the localization of cadherin in the upper tip-link density of the stereociliary membrane and for the initial mechanotransduction event in inner hair cells. Here the authors find that harmonin is involved in regulating the voltage-gated calcium channel for synaptic transmission in inner hair cell ribbon synapses.
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