Free urinary cortisol in the diagnosis of hypercorticism

: 24 hour urinary free cortisol has lower values in suspect obese patients compared to patients with Cushing's syndrome. The most favourable discriminatory border value of urinary cortisol is 100 micrograms/24 hours, giving the most valid differentiation of obese patients suspected for Cushing's syndrome from patients with hypercortisismus. Free cortisol has far expressive discriminatory value compared to 17-OHCS, and it is a good screening test in differential diagnosis of obese suspected patients from patients with Cushing's syndrome.