Clinical manifestations of blood cell parameters and inflammatory factors in 92 patients with COVID-19

BACKGROUND: Although there are many COVID-19 case series studies, few studies report the relationship between variations in blood cell parameters and inflammatory factors and disease severity This study aims to describe the dynamic trends in COVID-19 blood cell parameters and inflammatory factors METHODS: Ninety-two patients with confirmed COVID-19 at Jingzhou Central Hospital, Hubei Province, China, between January 23, 2020, and April 10, 2020, were enrolled Epidemiological data, clinical information, and laboratory test results were collected and analyzed RESULTS: As patient age increased, disease severity increased (P50 mg/L) 1 week after the initial decrease and continued to fluctuate at a high level Lymphocyte count (LYM#) in patients with severe and critical disease was significantly lower (1×10(9)/L), but patients with a poor prognosis continued to have a low LYM# CONCLUSIONS: CRP and LYM# showed strong correlation with disease progression, suggesting that these parameters could be used to monitor changes in patient condition