Correlations between cancellous bone architecture and its dynamic behaviour

Previous studies showed that in vivo evaluation of the fracture risk of cancellous bone can be assessed by identifying the relationships between its microarchitecture description extracted from clinical imaging and its mechanical properties. The mechanical properties under dynamic loadings (with and without confinement) were obtained and compared to quasi-static ones. The architectural parameters of each specimen were extracted from pQCT images and split into four groups: geometry, topology, connectivity and anisotropy. Results show that architectural parameters are strong determinants of mechanical behaviour for the different applied boundary conditions.