The Effects of Anticholinesterases and Atropine Derivatives on Visual Function in Human Subjects

Abstract : This project has been concerned with the action of anticholinesterases on vision and the degree of antagonism by atropine sulphate. The main test of visual function was the measurement of contrast sensitivity for the detection of a sine wave grating pattern of specified spatial frequency. The following experiments were undertaken on volunteer subjects, with their informed consent. Keywords: Pupils, Pyriodostigmine, Organophosphates, Prophylactics, Preventive medicine.