Bioassay‐guided separation of citreorosein and other oestrogenic compounds From Polygonum cuspidatum

Citreorosein was isolated from p. cuspidatum as a new oestrogenic compound, together with emodin and its glucoside, by silica gel column chromatography and preparative high-performance liquid chromatography sequentially. oestrogenic activity was determined by a recombinant yeast assay. copyright (c) 2008 john wiley & sons, ltd.