Antioxidant and Estrogen Like Activity of the Seed of Phoenix dactylifera L. Palm Growing in

2009 
Developing the Egyptian desert, especially the Egyptian Oases, is considered as one of the most important National goals. Thousands species of medicinal, aromatic and food plants grow in the Egyptian desert, creating a base of raw materials to be explored for drug and nutraceutical production. This work focused on an important biologically active plant growing in the Egyptian Oases which is Phoenix dactylifera L. Family Palmae. The non-polar and polar successive extracts of the seeds of Phoenix dactylifera L. which is widely distributed in El-Dakhla Oases were tested for the antioxidant activity by an in-vitro bioassay technique according to the β-carotene bleaching method, as well as for the estrogen-like- activity. The effect of the extracts on nutritional parameters was also assessed. Acute toxicity test of the non-polar and polar extracts was carried out. The results showed that both extracts have antioxidant and estrogen like activity with different degrees. Variable significant changes in the nutritional parameters were noticed. The non-polar and polar extracts showed complete safety. The bioactive fractions were subjected to a phytochemical examination and the biologically active compounds were identified by using different chromatographic techniques. Conclusion: Both non-polar and polar extracts of the seeds of the studied seeds of Phoenix dactylifera showed antioxidant and estrogen like activity with different degrees which may be attributed to the presence of sterols, tannins and flavonoids. Both extracts showed complete safety. (Report and Opinion. 2009;1(3):1-8). (ISSN: 1553-9873).
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