MP30-07 A MULTI-INSTITUTIONAL COMPARISON OF MULTI-PARAMETRIC MAGNETIC RESONANCE IMAGING PROSTATE FUSION BIOPSY METRICS: VALIDATION OF ACTIONABLE INTELLIGENCE METRIC AND REDUCTION METRIC

INTRODUCTION AND OBJECTIVES:The AIM and ReM were recently introduced to objectify fusion biopsy deliverables. The AIM metric affords a quantifiable assessment of when US/MRI fusion targeted biopsy (TB) technology provides actionable information over standard systematic template biopsy (SB). Meanwhile, ReM captures the cases where a SB could have been omitted. Here we applied these tools to two large tertiary center cohorts at disparate geographic locations, diverse patient populations, and different fusion biopsy methods to help understand how TB technology performs in varied clinical settings.METHODS:Using prospectively maintained databases, we identified men who underwent concomitant TB and SB using the UroNav System (InVivo®) at Fox Chase Cancer Center and the Artemis System (Eigen®) at Stanford University Medical Center. Actionable intelligence metric (AIM) was defined as all patients with higher Gleason score (GS) on TB (minimum GS ≥ 3+4=7) relative to SB divided by total patients with GS ≥ 3+4=7 CaP...