Pharmacokinetic aspects of geriatric therapy

: Some pharmacokinetic aspects of geriatric therapy were showed. Influence of alterations of physiological processes (changes of protein and lipid metabolism, failure of blood circulation and of renal function) in old age, on pharmacokinetics of drugs applied in geriatric pharmacotherapy (antibiotics, antiarrhythmic drugs, hypotensive drugs) were discussed. In this context, principles of rational pharmacotherapy of geriatric patients were proposed.