Crystal structure of (-)-(5R,7R,8S,9R,10S)-8-methyl-7-[(5 R)-3-methyl-2-oxooxolan-3-en-5-yl]-1-aza-6-oxatricyclo[8.3.0.0 5,9 ]tridecan-13-one monohydrate

The title compound, C17H23NO4·H2O, is an epimer of the natural tetra­cyclic alkaloid isosaxorumamide which consists of a fused 5–7–5 tricyclic core and a di­hydro­furan­one substituent. The terminal di­hydro­furan ring is essentially planar with a maximum deviation of 0.0273 (14) A from the mean plane and oxolane, azepane and pyrrolidine rings in the tricyclic ring system adopt twist, twist-chair and envelope forms, respectively. In the crystal, the amide and water mol­ecules are linked by O—H⋯O hydrogen bonds, forming a tape structure running along the b-axis direction. The tapes are further connected by C—H⋯O inter­actions into a three-dimensional architecture.