Analysis of heart rate variability in diabetic patients affected by autonomic cardiovascular neuropathy

In this paper, time- and frequency-domain parameters of the heart rate variability (HRV) are investigated in 45 Holter records for a group of diabetic patients with neuropathy (DNG) other group of diabetics without neuropathy (DWNG) and the control group (CG). Obtained results show that: 1) DNG vs. CG present significant differences of parameters in time- and frequency-domain at diurnal and nocturnal periods. 2) Only frequency-domain parameters can distinguish diabetic patients with and without neuropathy. 3) No differences have been appreciated between control and diabetic patients without neuropathy.