Genetic variants in immunogenic cell death (ICD) relating genes to predict outcome in metastatic colorectal cancer (mCRC): Data from FIRE-3, TRIBE and MAVERICC trials.

Hiroyuki Arai,Yi Xiao,Fotios Loupakis,Sebastian Stintzing,Jingyuan Wang,Francesca Battaglin,Shivani Soni,Wu Zhang,Christoph Mancao,Bodour Salhia,Shannon M. Mumenthaler,Daniel J. Weisenberger,Gangning Liang,Chiara Cremolini,Volker Heinemann,Alfredo Falcone,Joshua Millstein,Heinz-Josef Lenz

Genetic variants in immunogenic cell death (ICD) relating genes to predict outcome in metastatic colorectal cancer (mCRC): Data from FIRE-3, TRIBE and MAVERICC trials.

2020

Hiroyuki Arai
Yi Xiao
Fotios Loupakis
Sebastian Stintzing
Jingyuan Wang
Francesca Battaglin
Shivani Soni
Wu Zhang
Christoph Mancao
Bodour Salhia
Shannon M. Mumenthaler
Daniel J. Weisenberger
Gangning Liang
Chiara Cremolini
Volker Heinemann
Alfredo Falcone
Joshua Millstein
Heinz-Josef Lenz

187Background: ICD is an immune response against dead-cell antigens from cancer cells treated with cytotoxic and/or targeted therapies. Oxaliplatin (OHP) and cetuximab (Cet) are distinct drugs to e...

Keywords:

genetic variants
Internal medicine
Oncology
Tribe
Colorectal cancer
Medicine
Immunogenic cell death
Pathology
Gene
Cancer research
Cetuximab
Immune system
Antigen
Cancer cell
Oxaliplatin
Cytotoxic T cell

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