Catalytic Enantioselective Reformatsky Reaction of Alkyl Iodoacetate with Aldehydes Catalyzed by Chiral Schiff Base.

The catalytic enantioselective Reformatsky reaction with aldehydes catalyzed by chiral Schiff base 1 in the presence of Me2Zn under Ar–O2 atmosphere was achieved (up to 72% ee). This process provid...