A Recombinant Protein Based on Trypanosoma cruzi P21 Enhances Phagocytosis

Adele Aud Rodrigues,Tatiana Mordente Clemente,Marlus Alves dos Santos,Fabrício Castro Machado,Rafael Gonçalves Barbosa Gomes,Heline Hellen Teixeira Moreira,Mário Costa Cruz,Paula Cristina Brígido,Paulo César Santos,Flávia Alves Martins,Diana Bahia,Juliana Terzi Maricato,Luiz Mario Janini,Eduardo Horjales Reboredo,Renato Arruda Mortara,Claudio Vieira da Silva

A Recombinant Protein Based on Trypanosoma cruzi P21 Enhances Phagocytosis

2012

Adele Aud Rodrigues
Tatiana Mordente Clemente
Marlus Alves dos Santos
Fabrício Castro Machado
Rafael Gonçalves Barbosa Gomes
Heline Hellen Teixeira Moreira
Mário Costa Cruz
Paula Cristina Brígido
Paulo César Santos
Flávia Alves Martins
Diana Bahia
Juliana Terzi Maricato
Luiz Mario Janini
Eduardo Horjales Reboredo
Renato Arruda Mortara
Claudio Vieira da Silva

Background P21 is a secreted protein expressed in all developmental stages of Trypanosoma cruzi. The aim of this study was to determine the effect of the recombinant protein based on P21 (P21-His6) on inflammatory macrophages during phagocytosis.

Keywords:

Microbiology
Protozoan Proteins
Plasma protein binding
Cell biology
Trypanosoma cruzi
Phagocytosis
Recombinant DNA
Biology

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