Effect of a Combination of Antimicrobial Agents for the Treatment of Respiratory Disease in Cattle

Clinical effect of the administration of thiamphenicol (TP) and tylosin (TS) on bovine respiratory disease was investigated. Group I (n=64) were administered TP (10 mg/kg) and TS (4 mg/kg), group II (n=26) were given TP (5 mg/kg) and TS (2 mg/kg). For the control, TP group. (n=25) were given 20 mg/kg of TP and ampicillin group (n=23) were given 10 mg/kg of ampicillin. As a result, improvement of clinical findings was more rapid and the cure rate was significantly higher in group I compared to those in the other 3 groups. These results showed that a combination therapy with minimal basic doses of TP and TS is very effective for some respiratory diseases in cattle.