Famotidine for gastric radiography.

: The effectiveness of famotidine (20 mg) in suppressing nocturnal gastric secretion during preparation for gastric radiography was studied in 243 patients. The gastric juice volume was calculated from a single upright radiograph of the stomach. The overall percentage suppression of nocturnal gastric secretion by famotidine was 60%, while it was 47% in patients with upper gastrointestinal symptoms. Radiological examinations were of diagnostic quality in 82% of the controls and 91% of the famotidine group; excellent film were obtained in 45% and 3%, respectively. Our findings suggest that famotidine could be a useful pretreatment for barium meal examinations.