Capillary Zone Electrophoresis in a Comprehensive Screen for Basic Drugs in Whole Blood

Capillary zone electrophoresis (CZE) is shown to be capable of detecting a large number of basic drugs at concentrations considered to be forensically significant. A procedure for preparing extracts of whole blood for analysis by CZE is presented. Relative migration times are presented for over 400 drugs, analyzed using 100 mmol/L phosphate run buffer of pH 2.5 and pH 9.5