Prevention of Myopia Progression with 0.05% Atropine Solution

Aim: The aim of this study was to evaluate the efficacy of 0.05% atropine solution for controlling myopia progression in school-aged children. Results: This retrospective, case-control study enrolled myopic school-aged children who had presented at Kaohsiung Chang Gung Memorial Hospital (Kaohsiung, Taiwan) from 2001 to 2004. A group of 57 children (30 boys, 27 girls; 6–12 years of age) with regular follow-up was divided into a subgroup of 21 children (12 boys, 9 girls) who received atropine eyedrops (0.05%) every evening, and a subgroup of 36 children (18 boys, 18 girls), who remained untreated, served as controls. The changes in refractive status of 114 eyes in 57 children were collected and compared for patients treated with 0.05% atropine eyedrop and those without medical control. The initial spherical equivalent of refractive status range was between –0.5 and –5.5 D. Mean myopia progression for the group of patients treated with 0.05% atropine eyedrop (n = 21) was –0.28 ± 0.26 D/year, significantly lo...