A MetAP2 inhibitor blocks adipogenesis, yet improves glucose uptake in cells

Abu Bakkar Siddik,Bhaskar C. Das,Louis M. Weiss,Nikhil V. Dhurandhar,Vijay Hegde

A MetAP2 inhibitor blocks adipogenesis, yet improves glucose uptake in cells

2019

Abu Bakkar Siddik
Bhaskar C. Das
Louis M. Weiss
Nikhil V. Dhurandhar
Vijay Hegde

ABSTRACTAdipose tissue expansion involves angiogenesis to remodel its capillary network. The enzymemethionine aminopeptidase 2(MetAP2) promotes angiogenesis.MetAP2 inhibitors suppress angiogenesis ...

Keywords:

Glucose uptake
METAP2
Endocrinology
Adipogenesis
Internal medicine
Chemistry
Capillary network
Angiogenesis
Cell biology
lipid accumulation
Fumagillin
Aminopeptidase

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